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Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells

The kidney proximal tubule (PT) elaborates a uniquely high-capacity apical endocytic pathway to retrieve albumin and other proteins that escape the glomerular filtration barrier. Megalin and cubilin/amnionless (CUBAM) receptors engage Dab2 in these cells to mediate clathrin-dependent uptake of filte...

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Detalles Bibliográficos
Autores principales:	Rbaibi, Youssef, Long, Kimberly R., Shipman, Katherine E., Ren, Qidong, Baty, Catherine J., Kashlan, Ossama B., Weisz, Ora A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295476/ https://www.ncbi.nlm.nih.gov/pubmed/37126375 http://dx.doi.org/10.1091/mbc.E22-11-0510

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