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The role of kinetochore dynein in checkpoint silencing is restricted to disassembly of the corona

During mitosis, kinetochore–microtubule attachments are monitored by a molecular surveillance system known as the spindle assembly checkpoint. The prevailing model posits that dynein evicts checkpoint proteins (e.g., Mad1, Mad2) from stably attached kinetochores by transporting them away from kineto...

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Detalles Bibliográficos
Autores principales: Ide, Amy H., DeLuca, Keith F., Wiggan, O’Neil, Markus, Steven M., DeLuca, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295480/
https://www.ncbi.nlm.nih.gov/pubmed/37126397
http://dx.doi.org/10.1091/mbc.E23-04-0130