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Glutamylation is a negative regulator of microtubule growth
Microtubules are noncovalent polymers built from αβ-tubulin dimers. The disordered C-terminal tubulin tails are functionalized with multiple glutamate chains of variable lengths added and removed by tubulin tyrosine ligases (TTLLs) and carboxypeptidases (CCPs). Glutamylation is abundant on stable mi...
Autores principales: | Chen, Jiayi, Roll-Mecak, Antonina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295482/ https://www.ncbi.nlm.nih.gov/pubmed/37074962 http://dx.doi.org/10.1091/mbc.E23-01-0030 |
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