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Outer-arm dynein light chain LC1 is required for normal motor assembly kinetics, ciliary stability, and motility

Light chain 1 (LC1) is a highly conserved leucine-rich repeat protein associated with the microtubule-binding domain of the Chlamydomonas outer–dynein arm γ heavy chain. LC1 mutations in humans and trypanosomes lead to motility defects, while its loss in oomycetes results in aciliate zoospores. Here...

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Detalles Bibliográficos
Autores principales: Sakato-Antoku, Miho, King, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295483/
https://www.ncbi.nlm.nih.gov/pubmed/37133971
http://dx.doi.org/10.1091/mbc.E23-03-0104