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Regulation of neurofilament length and transport by a dynamic cycle of phospho-dependent polymer severing and annealing

Neurofilaments are cargoes of axonal transport which are unique among known intracellular cargoes in that they are long, flexible protein polymers. These polymers are transported into axons, where they accumulate in large numbers to drive the expansion of axon caliber, which is an important determin...

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Detalles Bibliográficos
Autores principales: Uchida, Atsuko, Peng, Juan, Brown, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295484/
https://www.ncbi.nlm.nih.gov/pubmed/36989035
http://dx.doi.org/10.1091/mbc.E23-01-0024