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3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer

SIMPLE SUMMARY: The cell architecture is created and maintained via adhesion molecules, called cadherins, that keep similar cells bound to each other. E-cadherin is a cadherin encoded by the CDH1 gene, essential in normal epithelia. P-cadherin, encoded by the CDH3 gene, exerts a similar function but...

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Detalles Bibliográficos
Autores principales: São José, Celina, Pereira, Carla, Ferreira, Marta, André, Ana, Osório, Hugo, Gullo, Irene, Carneiro, Fátima, Oliveira, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295718/
https://www.ncbi.nlm.nih.gov/pubmed/37372088
http://dx.doi.org/10.3390/biology12060803