Cargando…

3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer

SIMPLE SUMMARY: The cell architecture is created and maintained via adhesion molecules, called cadherins, that keep similar cells bound to each other. E-cadherin is a cadherin encoded by the CDH1 gene, essential in normal epithelia. P-cadherin, encoded by the CDH3 gene, exerts a similar function but...

Descripción completa

Detalles Bibliográficos
Autores principales:	São José, Celina, Pereira, Carla, Ferreira, Marta, André, Ana, Osório, Hugo, Gullo, Irene, Carneiro, Fátima, Oliveira, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295718/ https://www.ncbi.nlm.nih.gov/pubmed/37372088 http://dx.doi.org/10.3390/biology12060803

Ejemplares similares

FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts
por: Black, Markaisa, et al.
Publicado: (2018)

Role of an Atypical Cadherin Gene, Cdh23 in Prepulse Inhibition, and Implication of CDH23 in Schizophrenia
por: Balan, Shabeesh, et al.
Publicado: (2021)

CDH3/P-Cadherin regulates migration of HuCCT1 cholangiocarcinoma cells
por: Baek, Sungmin, et al.
Publicado: (2010)

Expression and Prognostic Significance of Cadherin 4 (CDH4) in Renal Cell Carcinoma
por: Zhou, Xiaohui, et al.
Publicado: (2020)

Comprehensive analysis of prognostic significance of cadherin (CDH) gene family in breast cancer
por: Ku, Su-Chi, et al.
Publicado: (2022)

CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer
por: Caldeira, José Roberto F, et al.
Publicado: (2006)

Role of the Adiponectin Binding Protein, T-Cadherin (Cdh13), in Allergic Airways Responses in Mice
por: Williams, Alison S., et al.
Publicado: (2012)

Role of the Adiponectin Binding Protein, T-Cadherin (cdh13), in Pulmonary Responses to Subacute Ozone
por: Kasahara, David I., et al.
Publicado: (2013)

Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity
por: Lachowicz-Scroggins, Marrah E., et al.
Publicado: (2018)

E-Cadherin (CDH1 Gene) Germline Mutations in Gastric Cancer: Evolutions and Innovations
por: Corso, Giovanni, et al.
Publicado: (2020)

Targeting N-cadherin (CDH2) and the malignant bone marrow microenvironment in acute leukaemia
por: Parker, Jessica, et al.
Publicado: (2023)

Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface
por: Karthikeyan, Subbulakshmi, et al.
Publicado: (2016)

CDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management
por: Shenoy, Santosh
Publicado: (2019)

P-Cadherin (CDH3) is overexpressed in colorectal tumors and has potential as a serum marker for colorectal cancer monitoring
por: Kumara, H.M.C. Shantha, et al.
Publicado: (2017)

Is Upregulation of BCL2 a Determinant of Tumor Development Driven by Inactivation of CDH1/E-Cadherin?
por: Karch, Inga, et al.
Publicado: (2013)

Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis
por: Kim, Sun A, et al.
Publicado: (2016)

CDH4 suppresses the progression of salivary adenoid cystic carcinoma via E-cadherin co-expression
por: Xie, Jian, et al.
Publicado: (2016)

Flying under the radar: CDH2 (N-cadherin), an important hub molecule in neurodevelopmental and neurodegenerative diseases
por: László, Zsófia I., et al.
Publicado: (2022)

The Role of Cadherin 12 (CDH12) in the Peritoneal Fluid among Patients with Endometriosis and Endometriosis-Related Infertility
por: Goławski, Ksawery, et al.
Publicado: (2022)

Landscape of Druggable Molecular Pathways Downstream of Genomic CDH1/Cadherin-1 Alterations in Gastric Cancer
por: Malpeli, Giorgio, et al.
Publicado: (2022)

Association of e-cadherin gene CDH1 polymorphism -160 C/A with susceptibility to develop vitiligo()
por: Kubelis-López, David Emmanuel, et al.
Publicado: (2023)

Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer
por: Khouzam, Raefa Abou, et al.
Publicado: (2016)

CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice
por: Halperin, D., et al.
Publicado: (2021)

Analysis of E-cadherin (CDH1) Gene Polymorphism and Its Association with Cervical Cancer Risk in Bangladeshi Women
por: Rahman, Md. Abdur, et al.
Publicado: (2023)

Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin
por: Förster, Alisa, et al.
Publicado: (2021)

CDH1 (E-cadherin) Gene Methylation in Human Breast Cancer: Critical Appraisal of a Long and Twisted Story
por: Bücker, Lara, et al.
Publicado: (2022)

Cadherin-16 (CDH16) immunohistochemistry: a useful diagnostic tool for renal cell carcinoma and papillary carcinomas of the thyroid
por: Lennartz, Maximilian, et al.
Publicado: (2023)

CDH3/P-cadherin overexpression in breast carcinomas: its regulatory mechanisms, the role in cell invasion, and the association with cancer stem cell properties
por: Paredes, Joana
Publicado: (2010)

Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13)
por: Hart, Amy B., et al.
Publicado: (2012)

Quantification of mutant E-cadherin using bioimaging analysis of in situ fluorescence microscopy. A new approach to CDH1 missense variants
por: Sanches, João Miguel, et al.
Publicado: (2015)

Worsened outcome in patients with pancreatic ductal carcinoma on long-term diabetes: association with E-cadherin1 (CDH1) promoter methylation
por: Saito, Takeshi, et al.
Publicado: (2017)

Genetic and Epigenetic Alterations of CDH1 Regulatory Regions in Hereditary and Sporadic Gastric Cancer
por: Tedaldi, Gianluca, et al.
Publicado: (2021)

CCAAT/Enhancer Binding Protein β (C/EBPβ) Isoforms as Transcriptional Regulators of the Pro-Invasive CDH3/P-Cadherin Gene in Human Breast Cancer Cells
por: Albergaria, André, et al.
Publicado: (2013)

The CDH patient perspective journey
por: Power, Beverley
Publicado: (2023)

A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: A case control study in an Italian population
por: Nasri, Soroush, et al.
Publicado: (2008)

Rare familial 16q21 microdeletions under a linkage peak implicate cadherin 8 (CDH8) in susceptibility to autism and learning disability
por: Pagnamenta, Alistair T, et al.
Publicado: (2010)

Epithelial-mesenchymal transition and nuclear β-catenin induced by conditional intestinal disruption of Cdh1 with Apc is E-cadherin EC1 domain dependent
por: Matheson, Julia, et al.
Publicado: (2016)

p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth
por: Ouyang, Hanyue, et al.
Publicado: (2020)

Clinical Relevance of CDH1 and CDH13 DNA-Methylation in Serum of Cervical Cancer Patients
por: Abudukadeer, Abida, et al.
Publicado: (2012)

Control of CDH1/E-Cadherin Gene Expression and Release of a Soluble Form of E-Cadherin in SARS-CoV-2 Infected Caco-2 Intestinal Cells: Physiopathological Consequences for the Intestinal Forms of COVID-19
por: Osman, Ikram Omar, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_blaai1f7u41km95qc99925vkpo