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Establishment of a Perfusion Process with Antibody-Producing CHO Cells Using a 3D-Printed Microfluidic Spiral Separator with Web-Based Flow Control

Monoclonal antibodies are increasingly dominating the market for human therapeutic and diagnostic agents. For this reason, continuous methods—such as perfusion processes—are being explored and optimized in an ongoing effort to increase product yields. Unfortunately, many established cell retention d...

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Detalles Bibliográficos
Autores principales: Schellenberg, Jana, Dehne, Michaela, Lange, Ferdinand, Scheper, Thomas, Solle, Dörte, Bahnemann, Janina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295792/
https://www.ncbi.nlm.nih.gov/pubmed/37370588
http://dx.doi.org/10.3390/bioengineering10060656