Insight into the Mode of Action of 8-Hydroxyquinoline-Based Blockers on the Histamine Receptor 2

Histamine receptor 2 (HR(H2)) blockers are used to treat peptic ulcers and gastric reflux. Chlorquinaldol and chloroxine, which contain an 8-hydroxyquinoline (8HQ) core, have recently been identified as blocking HR(H2). To gain insight into the mode of action of 8HQ-based blockers, here, we leverage...

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Detalles Bibliográficos
Autores principales: Patel, Amisha, Marquez-Gomez, Paola L., Torp, Lily R., Gao, Lily, Peralta-Yahya, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295836/
https://www.ncbi.nlm.nih.gov/pubmed/37366936
http://dx.doi.org/10.3390/bios13060571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295836/
https://www.ncbi.nlm.nih.gov/pubmed/37366936
http://dx.doi.org/10.3390/bios13060571

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