A Novel MDM2-Binding Chalcone Induces Apoptosis of Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) represents ~90% of all oral cancers, being the eighth most common cancer in men. The overall 5-year survival rate is only 39% for metastatic cancers, and currently used chemotherapeutics can cause important side effects. Thus, there is an urgency in developing new...

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Detalles Bibliográficos
Autores principales: Wermelinger, Guilherme Freimann, Rubini, Lucas, da Fonseca, Anna Carolina Carvalho, Ouverney, Gabriel, de Oliveira, Rafael P. R. F., de Souza, Acácio S., Forezi, Luana S. M., Limaverde-Sousa, Gabriel, Pinheiro, Sergio, Robbs, Bruno Kaufmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295897/
https://www.ncbi.nlm.nih.gov/pubmed/37371806
http://dx.doi.org/10.3390/biomedicines11061711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295897/
https://www.ncbi.nlm.nih.gov/pubmed/37371806
http://dx.doi.org/10.3390/biomedicines11061711

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