METTL3-Modulated circUHRF2 Promotes Colorectal Cancer Stemness and Metastasis through Increasing DDX27 mRNA Stability by Recruiting IGF2BP1

SIMPLE SUMMARY: Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide, and no cure exists for most patients at advanced stages with distant metastasis. CircUHRF2 has been aberrantly expressed in CRC, but its role in CRC growth and metastasis remains largely unclear. This stud...

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Detalles Bibliográficos
Autores principales: Chen, Miao, Tian, Buning, Hu, Gui, Guo, Yihang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295973/
https://www.ncbi.nlm.nih.gov/pubmed/37370759
http://dx.doi.org/10.3390/cancers15123148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295973/
https://www.ncbi.nlm.nih.gov/pubmed/37370759
http://dx.doi.org/10.3390/cancers15123148

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