Simultaneous Inhibition of Mcl-1 and Bcl-2 Induces Synergistic Cell Death in Hepatocellular Carcinoma

Despite the recent approval of new therapies, the prognosis for patients with hepatocellular carcinoma (HCC) remains poor. There is a clinical need for new highly effective therapeutic options. Here, we present a combined application of BH3-mimetics as a potential new treatment option for HCC. BH3-m...

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Detalles Bibliográficos
Autores principales: Michalski, Marlen, Bauer, Magdalena, Walz, Franziska, Tümen, Deniz, Heumann, Philipp, Stöckert, Petra, Gunckel, Manuela, Kunst, Claudia, Kandulski, Arne, Schmid, Stephan, Müller, Martina, Gülow, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295989/
https://www.ncbi.nlm.nih.gov/pubmed/37371761
http://dx.doi.org/10.3390/biomedicines11061666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295989/
https://www.ncbi.nlm.nih.gov/pubmed/37371761
http://dx.doi.org/10.3390/biomedicines11061666

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