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Molecular Biophysics of Class A G Protein Coupled Receptors–Lipids Interactome at a Glance—Highlights from the A(2A) Adenosine Receptor

G protein-coupled receptors (GPCRs) are embedded in phospholipid membrane bilayers with cholesterol representing 34% of the total lipid content in mammalian plasma membranes. Membrane lipids interact with GPCRs structures and modulate their function and drug-stimulated signaling through conformation...

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Detalles Bibliográficos
Autores principales: Tzortzini, Efpraxia, Kolocouris, Antonios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296092/
https://www.ncbi.nlm.nih.gov/pubmed/37371538
http://dx.doi.org/10.3390/biom13060957