K-Ras Binds Calmodulin-Related Centrin1 with Potential Implications for K-Ras Driven Cancer Cell Stemness

SIMPLE SUMMARY: Trafficking chaperones facilitate the spatio-temporal distribution pattern of proteins inside cells. In the case of the membrane-anchored protein Ras, trafficking chaperones typically bind to the C-terminal farnesyl-moiety. Thus shielded from the aqueous environment, Ras can diffuse...

Descripción completa

Detalles Bibliográficos
Autores principales: Manoharan, Ganesh babu, Laurini, Christina, Bottone, Sara, Ben Fredj, Nesrine, Abankwa, Daniel Kwaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296094/
https://www.ncbi.nlm.nih.gov/pubmed/37370697
http://dx.doi.org/10.3390/cancers15123087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296094/
https://www.ncbi.nlm.nih.gov/pubmed/37370697
http://dx.doi.org/10.3390/cancers15123087

Ejemplares similares