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Reduction of Tumor Growth with RNA-Targeting Treatment of the NAB2–STAT6 Fusion Transcript in Solitary Fibrous Tumor Models

SIMPLE SUMMARY: Solitary fibrous tumor (SFT) is a soft-tissue sarcoma occurring in adults and infants. This nonhereditary cancer is the result of an environmental intrachromosomal gene fusion between NAB2 and STAT6 on chromosome 12. Either surgery or radiation is the first line of treatment for this...

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Detalles Bibliográficos
Autores principales: Li, Yi, Nguyen, John T., Ammanamanchi, Manasvini, Zhou, Zikun, Harbut, Elijah F., Mondaza-Hernandez, Jose L., Meyer, Clark A., Moura, David S., Martin-Broto, Javier, Hayenga, Heather N., Bleris, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296122/
https://www.ncbi.nlm.nih.gov/pubmed/37370737
http://dx.doi.org/10.3390/cancers15123127