Bcl-xL Is Spontaneously Inserted into Preassembled Nanodiscs and Stimulates Bax Insertion in a Cell-Free Protein Synthesis System

The antiapoptotic protein Bcl-xL is a major regulator of cell death and survival, but many aspects of its functions remain elusive. It is mostly localized in the mitochondrial outer membrane (MOM) owing to its C-terminal hydrophobic α-helix. In order to gain further information about its membrane or...

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Detalles Bibliográficos
Autores principales: Rouchidane Eyitayo, Akandé, Boudier-Lemosquet, Axel, Chaignepain, Stéphane, Priault, Muriel, Manon, Stéphen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296133/
https://www.ncbi.nlm.nih.gov/pubmed/37371456
http://dx.doi.org/10.3390/biom13060876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296133/
https://www.ncbi.nlm.nih.gov/pubmed/37371456
http://dx.doi.org/10.3390/biom13060876

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