Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice

Doxorubicin (DOX) and mitoxantrone (MTX) are classical chemotherapeutic agents used in cancer that induce similar clinical cardiotoxic effects, although it is not clear if they share similar underlying molecular mechanisms. We aimed to assess the effects of DOX and MTX on the cardiac remodeling, foc...

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Detalles Bibliográficos
Autores principales: Brandão, Sofia Reis, Reis-Mendes, Ana, Duarte-Araújo, Margarida, Neuparth, Maria João, Rocha, Hugo, Carvalho, Félix, Ferreira, Rita, Costa, Vera Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296231/
https://www.ncbi.nlm.nih.gov/pubmed/37371499
http://dx.doi.org/10.3390/biom13060921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296231/
https://www.ncbi.nlm.nih.gov/pubmed/37371499
http://dx.doi.org/10.3390/biom13060921

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