HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter

HIV-1 infection leads to a gradual loss of T helper cells, chronic immune activation, and eventual immune system breakdown. HIV-1 causes deregulation of the expression of IL-2, a cytokine important for T helper cell growth and survival, which is downregulated in HIV-1 patients. The present study add...

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Detalles Bibliográficos
Autores principales: Anastasopoulou, Spyridoula, Georgakopoulos, Tassos, Mouzaki, Athanasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296241/
https://www.ncbi.nlm.nih.gov/pubmed/37371461
http://dx.doi.org/10.3390/biom13060881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296241/
https://www.ncbi.nlm.nih.gov/pubmed/37371461
http://dx.doi.org/10.3390/biom13060881

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