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Mannose-Binding Lectin Reduces Oxidized Low-Density Lipoprotein Induced Vascular Endothelial Cells Injury by Inhibiting LOX1-ox-LDL Binding and Modulating Autophagy

Objective: To investigate the role of mannose-binding lectin (MBL) in modulating autophagy and protecting endothelial cells (ECs) from oxidized low-density lipoprotein (ox-LDL)-induced injury. Methods: Serum MBL concentration and carotid intima-media thickness (cIMT) were measured in 94 obese and 10...

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Detalles Bibliográficos
Autores principales: Zhou, Xuelian, Chen, Xuefeng, Zhang, Li, Yuan, Jinna, Lin, Hu, Zhu, Mingqiang, Xu, Xiaoqin, Dong, Guanping, Fu, Junfen, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296346/
https://www.ncbi.nlm.nih.gov/pubmed/37371838
http://dx.doi.org/10.3390/biomedicines11061743