Spatial Heterogeneity in Cytoskeletal Mechanics Response to TGF-β1 and Hypoxia Mediates Partial Epithelial-to-Meshenchymal Transition in Epithelial Ovarian Cancer Cells

SIMPLE SUMMARY: One major challenge to understanding and targeting deadly epithelial ovarian cancer is the heterogeneous nature of the disease, including intrinsic physical and genetic differences in cells and differences in the spatial microenvironmental cues in the tumor. In this study, we show th...

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Detalles Bibliográficos
Autores principales: Ghosh, Deepraj, Hsu, Jeffrey, Soriano, Kylen, Peña, Carolina Mejia, Lee, Amy H., Dizon, Don S., Dawson, Michelle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296400/
https://www.ncbi.nlm.nih.gov/pubmed/37370796
http://dx.doi.org/10.3390/cancers15123186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296400/
https://www.ncbi.nlm.nih.gov/pubmed/37370796
http://dx.doi.org/10.3390/cancers15123186

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