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Methyl-Thiol-Bridged Oxadiazole and Triazole Heterocycles as Inhibitors of NF-κB in Chronic Myelogenous Leukemia Cells

Nuclear factor kappa beta (NF-κB) is a transcriptional factor that plays a crucial role in regulating cancer cell proliferation. Therefore, the inhibition of NF-κB activity by small molecules may be beneficial in cancer therapy. In this report, methyl-thiol-bridged oxadiazole and triazole heterocycl...

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Detalles Bibliográficos
Autores principales: Basappa, Basappa, Jung, Young Yun, Ravish, Akshay, Xi, Zhang, Swamynayaka, Ananda, Madegowda, Mahendra, Pandey, Vijay, Lobie, Peter E., Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296415/
https://www.ncbi.nlm.nih.gov/pubmed/37371757
http://dx.doi.org/10.3390/biomedicines11061662