Cargando…

TP53 Mutations in AML Patients Are Associated with Dismal Clinical Outcome Irrespective of Frontline Induction Regimen and Allogeneic Hematopoietic Cell Transplantation

SIMPLE SUMMARY: TP53 mutations are adverse-risk genetic aberrations in acute myeloid leukemia (AML). The optimal treatment approach in patients with TP53-mutated (TP53(MUT)) AML remains unclear. We aimed to evaluate the prognostic implications of different frontline treatment strategies and transpla...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Davidson, Zarif, Mojgan, Zhou, Qianghua, Capo-Chichi, José-Mario, Schuh, Andre, Minden, Mark D., Atenafu, Eshetu G., Kumar, Rajat, Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296444/
https://www.ncbi.nlm.nih.gov/pubmed/37370821
http://dx.doi.org/10.3390/cancers15123210