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TP53 Mutations in AML Patients Are Associated with Dismal Clinical Outcome Irrespective of Frontline Induction Regimen and Allogeneic Hematopoietic Cell Transplantation

SIMPLE SUMMARY: TP53 mutations are adverse-risk genetic aberrations in acute myeloid leukemia (AML). The optimal treatment approach in patients with TP53-mutated (TP53(MUT)) AML remains unclear. We aimed to evaluate the prognostic implications of different frontline treatment strategies and transpla...

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Detalles Bibliográficos
Autores principales:	Zhao, Davidson, Zarif, Mojgan, Zhou, Qianghua, Capo-Chichi, José-Mario, Schuh, Andre, Minden, Mark D., Atenafu, Eshetu G., Kumar, Rajat, Chang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296444/ https://www.ncbi.nlm.nih.gov/pubmed/37370821 http://dx.doi.org/10.3390/cancers15123210

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