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Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus
Interferon-induced transmembrane proteins (IFITMs) block the fusion of diverse enveloped viruses, likely through increasing the cell membrane’s rigidity. Previous studies have reported that the antiviral activity of the IFITM family member, IFITM3, is antagonized by cell pretreatment with rapamycin...
Autores principales: | Prikryl, David, Marin, Mariana, Desai, Tanay M., Du, Yuhong, Fu, Haian, Melikyan, Gregory B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296495/ https://www.ncbi.nlm.nih.gov/pubmed/37371517 http://dx.doi.org/10.3390/biom13060937 |
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