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The ST2/IL-33 Pathway in Adult and Paediatric Heart Disease and Transplantation

ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous intracytoplasmic mediators following the binding with ST2L and IL-1RAcP, leading to nuclear signal and cardiovascular effect. Di...

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Detalles Bibliográficos
Autores principales: Brunetti, Giacomina, Barile, Barbara, Nicchia, Grazia Paola, Onorati, Francesco, Luciani, Giovanni Battista, Galeone, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296498/
https://www.ncbi.nlm.nih.gov/pubmed/37371771
http://dx.doi.org/10.3390/biomedicines11061676