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RUNX Family as a Promising Biomarker and a Therapeutic Target in Bone Cancers: A Review on Its Molecular Mechanism(s) behind Tumorigenesis

SIMPLE SUMMARY: The transcription factor RUNX family plays a crucial role in the formation of osteoblasts from bone marrow mesenchymal stem cells, contributing to bone development. However, emerging evidence suggests its involvement in tumor biology and cancer progression. In particular, the RUNX fa...

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Detalles Bibliográficos
Autores principales: Vimalraj, Selvaraj, Sekaran, Saravanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296500/
https://www.ncbi.nlm.nih.gov/pubmed/37370857
http://dx.doi.org/10.3390/cancers15123247