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Alternative Lengthening of Telomeres in Pediatric High-Grade Glioma and Therapeutic Implications

SIMPLE SUMMARY: Pediatric high-grade gliomas (pHGGs) are highly aggressive tumors with a dismal prognosis despite multimodal therapy including surgery, radiation therapy and chemotherapy, underscoring the urgent need to develop novel therapeutic strategies. During tumor development, cells achieve im...

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Detalles Bibliográficos
Autores principales: Umaru, Banlanjo, Sengupta, Satarupa, Senthil Kumar, Shiva, Drissi, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296514/
https://www.ncbi.nlm.nih.gov/pubmed/37370681
http://dx.doi.org/10.3390/cancers15123070