Chromosomal Aberration t(14;17)(q32;q21) Simultaneously Activates HOXB5 and miR10a in Triple-Hit B-Cell Lymphoma

BCL2, BCL6 and MYC are major oncogenes in B-cell lymphoma. Their aberrant activation frequently occurs via chromosomal translocations which juxtapose light or heavy chain immunoglobulin (IG) genes to BCL2 and MYC or fuse diverse partner genes with BCL6. So-called double-hit lymphomas usually carry B...

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Detalles Bibliográficos
Autores principales: Nagel, Stefan, Pommerenke, Claudia, Meyer, Corinna, Kaufmann, Maren, MacLeod, Roderick A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296542/
https://www.ncbi.nlm.nih.gov/pubmed/37371852
http://dx.doi.org/10.3390/biomedicines11061758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296542/
https://www.ncbi.nlm.nih.gov/pubmed/37371852
http://dx.doi.org/10.3390/biomedicines11061758

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