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RPS27a and RPL40, Which Are Produced as Ubiquitin Fusion Proteins, Are Not Essential for p53 Signalling

Two of the four human ubiquitin-encoding genes express ubiquitin as an N-terminal fusion precursor polypeptide, with either ribosomal protein (RP) RPS27a or RPL40 at the C-terminus. RPS27a and RPL40 have been proposed to be important for the induction of the tumour suppressor p53 in response to defe...

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Detalles Bibliográficos
Autores principales: Eastham, Matthew John, Pelava, Andria, Wells, Graeme Raymond, Watkins, Nicholas James, Schneider, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296562/
https://www.ncbi.nlm.nih.gov/pubmed/37371478
http://dx.doi.org/10.3390/biom13060898