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Recombinant α(1)-Microglobulin (rA1M) Protects against Hematopoietic and Renal Toxicity, Alone and in Combination with Amino Acids, in a (177)Lu-DOTATATE Mouse Radiation Model

(177)Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) is used clinically to treat metastasized or unresectable neuroendocrine tumors (NETs). Although (177)Lu-DOTATATE is mostly well tolerated in patients, bone marrow suppression and long-term renal toxicity are still side effects that should...

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Detalles Bibliográficos
Autores principales: Alattar, Abdul Ghani, Kristiansson, Amanda, Karlsson, Helena, Vallius, Suvi, Ahlstedt, Jonas, Forssell-Aronsson, Eva, Åkerström, Bo, Strand, Sven-Erik, Flygare, Johan, Gram, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296637/
https://www.ncbi.nlm.nih.gov/pubmed/37371508
http://dx.doi.org/10.3390/biom13060928