APOE Peripheral and Brain Impact: APOE4 Carriers Accelerate Their Alzheimer Continuum and Have a High Risk of Suicide in PM(2.5) Polluted Cities

This Review emphasizes the impact of APOE4—the most significant genetic risk factor for Alzheimer’s disease (AD)—on peripheral and neural effects starting in childhood. We discuss major mechanistic players associated with the APOE alleles’ effects in humans to understand their impact from conception...

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Detalles Bibliográficos
Autores principales: Calderón-Garcidueñas, Lilian, Hernández-Luna, Jacqueline, Aiello-Mora, Mario, Brito-Aguilar, Rafael, Evelson, Pablo A., Villarreal-Ríos, Rodolfo, Torres-Jardón, Ricardo, Ayala, Alberto, Mukherjee, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296707/
https://www.ncbi.nlm.nih.gov/pubmed/37371506
http://dx.doi.org/10.3390/biom13060927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296707/
https://www.ncbi.nlm.nih.gov/pubmed/37371506
http://dx.doi.org/10.3390/biom13060927

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