Generation and Characterization of a Zebrafish Model for ADGRV1-Associated Retinal Dysfunction Using CRISPR/Cas9 Genome Editing Technology

Worldwide, around 40,000 people progressively lose their eyesight as a consequence of retinitis pigmentosa (RP) caused by pathogenic variants in the ADGRV1 gene, for which currently no treatment options exist. A model organism that mimics the human phenotype is essential to unravel the exact pathoph...

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Detalles Bibliográficos
Autores principales: Stemerdink, Merel, Broekman, Sanne, Peters, Theo, Kremer, Hannie, de Vrieze, Erik, van Wijk, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296736/
https://www.ncbi.nlm.nih.gov/pubmed/37371069
http://dx.doi.org/10.3390/cells12121598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296736/
https://www.ncbi.nlm.nih.gov/pubmed/37371069
http://dx.doi.org/10.3390/cells12121598

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