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Graft-Derived Cell-Free DNA Quantification following Liver Transplantation Using Tissue-Specific DNA Methylation and Donor-Specific Genotyping Techniques: An Orthogonal Comparison Study

Background: Graft-derived cell-free DNA (gdcfDNA) analysis has shown promise as a non-invasive tool for monitoring organ health following solid organ transplantation. A number of gdcfDNA analysis techniques have been described; however, the majority rely on sequencing or prior genotyping to detect d...

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Detalles Bibliográficos
Autores principales: Cox, Daniel R. A., McClure, Tess, Zhang, Fan, Wong, Boris Ka Leong, Testro, Adam, Goh, Su Kah, Muralidharan, Vijayaragavan, Dobrovic, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296814/
https://www.ncbi.nlm.nih.gov/pubmed/37367181
http://dx.doi.org/10.3390/epigenomes7020011