Human Adult Renal Progenitor Cells Prevent Cisplatin-Nephrotoxicity by Inducing CYP1B1 Overexpression and miR-27b-3p Down-Regulation through Extracellular Vesicles

Cisplatin is one of the most effective chemotherapeutic agents strongly associated with nephrotoxicity. Tubular adult renal progenitor cells (tARPC) can regenerate functional tubules and participate in the repair processes after cisplatin exposition. This study investigated the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Franzin, Rossana, Stasi, Alessandra, De Palma, Giuseppe, Picerno, Angela, Curci, Claudia, Sebastiano, Serena, Campioni, Monica, Cicirelli, Antonella, Rizzo, Alessandro, Di Lorenzo, Vito Francesco, Pontrelli, Paola, Pertosa, Giovanni Battista, Castellano, Giuseppe, Gesualdo, Loreto, Sallustio, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296841/
https://www.ncbi.nlm.nih.gov/pubmed/37371125
http://dx.doi.org/10.3390/cells12121655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296841/
https://www.ncbi.nlm.nih.gov/pubmed/37371125
http://dx.doi.org/10.3390/cells12121655

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