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Human Adult Renal Progenitor Cells Prevent Cisplatin-Nephrotoxicity by Inducing CYP1B1 Overexpression and miR-27b-3p Down-Regulation through Extracellular Vesicles
Cisplatin is one of the most effective chemotherapeutic agents strongly associated with nephrotoxicity. Tubular adult renal progenitor cells (tARPC) can regenerate functional tubules and participate in the repair processes after cisplatin exposition. This study investigated the molecular mechanisms...
Autores principales: | Franzin, Rossana, Stasi, Alessandra, De Palma, Giuseppe, Picerno, Angela, Curci, Claudia, Sebastiano, Serena, Campioni, Monica, Cicirelli, Antonella, Rizzo, Alessandro, Di Lorenzo, Vito Francesco, Pontrelli, Paola, Pertosa, Giovanni Battista, Castellano, Giuseppe, Gesualdo, Loreto, Sallustio, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296841/ https://www.ncbi.nlm.nih.gov/pubmed/37371125 http://dx.doi.org/10.3390/cells12121655 |
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