TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo

The role of TREM2 in Alzheimer’s disease (AD) is not fully understood. Previous studies investigating the effect of TREM2 deletion on tauopathy mouse models without the contribution of b-amyloid have focused only on tau overexpression models. Herein, we investigated the effects of TREM2 deficiency o...

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Detalles Bibliográficos
Autores principales: Lee-Gosselin, Audrey, Jury-Garfe, Nur, You, Yanwen, Dabin, Luke, Soni, Disha, Dutta, Sayan, Rochet, Jean-Christophe, Kim, Jungsu, Oblak, Adrian L., Lasagna-Reeves, Cristian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296847/
https://www.ncbi.nlm.nih.gov/pubmed/37371067
http://dx.doi.org/10.3390/cells12121597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296847/
https://www.ncbi.nlm.nih.gov/pubmed/37371067
http://dx.doi.org/10.3390/cells12121597

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