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PD-L1’s Role in Preventing Alloreactive T Cell Responses Following Hematopoietic and Organ Transplant

Over the past decade, Programmed Death-Ligand 1 (PD-L1) has emerged as a prominent target for cancer immunotherapies. However, its potential as an immunosuppressive therapy has been limited. In this review, we present the immunological basis of graft rejection and graft-versus-host disease (GVHD), f...

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Detalles Bibliográficos
Autores principales: Handelsman, Shane, Overbey, Juliana, Chen, Kevin, Lee, Justin, Haj, Delour, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296912/
https://www.ncbi.nlm.nih.gov/pubmed/37371079
http://dx.doi.org/10.3390/cells12121609