Myelin Disruption, Neuroinflammation, and Oxidative Stress Induced by Sulfite in the Striatum of Rats Are Mitigated by the pan-PPAR agonist Bezafibrate

Sulfite predominantly accumulates in the brain of patients with isolated sulfite oxidase (ISOD) and molybdenum cofactor (MoCD) deficiencies. Patients present with severe neurological symptoms and basal ganglia alterations, the pathophysiology of which is not fully established. Therapies are ineffect...

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Detalles Bibliográficos
Autores principales: Glänzel, Nícolas Manzke, Parmeggiani, Belisa, Grings, Mateus, Seminotti, Bianca, Brondani, Morgana, Bobermin, Larissa D., Ribeiro, César A. J., Quincozes-Santos, André, Vockley, Jerry, Leipnitz, Guilhian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296939/
https://www.ncbi.nlm.nih.gov/pubmed/37371027
http://dx.doi.org/10.3390/cells12121557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296939/
https://www.ncbi.nlm.nih.gov/pubmed/37371027
http://dx.doi.org/10.3390/cells12121557

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