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Impact of HepG2 Cells Glutathione Depletion on Neutral Sphingomyelinases mRNA Levels and Activity

Liver cancer is a prevalent form of cancer worldwide. While research has shown that increasing sphingomyelin (SM) hydrolysis by activating the cell surface membrane-associated neutral sphingomyelinase 2 (nSMase2) can control cell proliferation and apoptosis, the role of total glutathione depletion i...

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Detalles Bibliográficos
Autores principales: Gamal, Marie, Tallima, Hatem, Azzazy, Hassan M. E., Abdelnaser, Anwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296953/
https://www.ncbi.nlm.nih.gov/pubmed/37367067
http://dx.doi.org/10.3390/cimb45060318