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Impact of HepG2 Cells Glutathione Depletion on Neutral Sphingomyelinases mRNA Levels and Activity
Liver cancer is a prevalent form of cancer worldwide. While research has shown that increasing sphingomyelin (SM) hydrolysis by activating the cell surface membrane-associated neutral sphingomyelinase 2 (nSMase2) can control cell proliferation and apoptosis, the role of total glutathione depletion i...
Autores principales: | Gamal, Marie, Tallima, Hatem, Azzazy, Hassan M. E., Abdelnaser, Anwar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296953/ https://www.ncbi.nlm.nih.gov/pubmed/37367067 http://dx.doi.org/10.3390/cimb45060318 |
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