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Genomic Mapping of Epidermal Growth Factor Receptor and Mesenchymal–Epithelial Transition-Up-Regulated Tumors Identifies Novel Therapeutic Opportunities

SIMPLE SUMMARY: The identification of proteins in the cellular membrane of the tumoral cell is a key to the design and guidance of therapeutic agents. Recently, a bi-specific antibody termed amivantamab, targeting epidermal growth factor receptor (EGFR) and mesenchymal–epithelial transition factor (...

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Detalles Bibliográficos
Autores principales: Paniagua-Herranz, Lucía, Doger, Bernard, Díaz-Tejeiro, Cristina, Sanvicente, Adrián, Nieto-Jiménez, Cristina, Moreno, Víctor, Pérez Segura, Pedro, Gyorffy, Balazs, Calvo, Emiliano, Ocana, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297015/
https://www.ncbi.nlm.nih.gov/pubmed/37370859
http://dx.doi.org/10.3390/cancers15123250