Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights

RalBP1 (Rlip) is a stress-activated protein that is believed to play a large role in aging and neurodegenerative diseases such as Alzheimer’s disease (AD) and other tauopathies. The purpose of our study was to understand the role of Rlip in mutant Tau-expressed immortalized hippocampal HT22 cells. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Reddy, P. Hemachandra, Kshirsagar, Sudhir, Bose, Chhanda, Pradeepkiran, Jangampalli Adi, Hindle, Ashly, Singh, Sharda P., Reddy, Arubala P., Baig, Javaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297078/
https://www.ncbi.nlm.nih.gov/pubmed/37371116
http://dx.doi.org/10.3390/cells12121646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297078/
https://www.ncbi.nlm.nih.gov/pubmed/37371116
http://dx.doi.org/10.3390/cells12121646

Ejemplares similares