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Rlip Reduction Induces Oxidative Stress and Mitochondrial Dysfunction in Mutant Tau-Expressed Immortalized Hippocampal Neurons: Mechanistic Insights
RalBP1 (Rlip) is a stress-activated protein that is believed to play a large role in aging and neurodegenerative diseases such as Alzheimer’s disease (AD) and other tauopathies. The purpose of our study was to understand the role of Rlip in mutant Tau-expressed immortalized hippocampal HT22 cells. I...
Autores principales: | Reddy, P. Hemachandra, Kshirsagar, Sudhir, Bose, Chhanda, Pradeepkiran, Jangampalli Adi, Hindle, Ashly, Singh, Sharda P., Reddy, Arubala P., Baig, Javaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297078/ https://www.ncbi.nlm.nih.gov/pubmed/37371116 http://dx.doi.org/10.3390/cells12121646 |
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