Development of a Detection System for ESR1 Mutations in Circulating Tumour DNA Using PNA-LNA-Mediated PCR Clamping

Although circulating tumour DNA (ctDNA)-based next-generation sequencing (NGS) is a less invasive method for assessing ESR1 mutations that are essential mechanisms of endocrine therapy resistance in patients with oestrogen receptor-positive breast cancer, adequate amounts of DNA are required to asse...

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Detalles Bibliográficos
Autores principales: Kojima, Yuki, Noguchi, Emi, Yoshino, Tomomi, Yagishita, Shigehiro, Yazaki, Shu, Okuma, Hitomi S., Nishikawa, Tadaaki, Tanioka, Maki, Sudo, Kazuki, Shimoi, Tatsunori, Kazama, Ayaka, Terasaki, Hiroshi, Asano, Sachiro, Fujiwara, Yasuhiro, Hamada, Akinobu, Tamura, Kenji, Yonemori, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297184/
https://www.ncbi.nlm.nih.gov/pubmed/37370935
http://dx.doi.org/10.3390/diagnostics13122040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297184/
https://www.ncbi.nlm.nih.gov/pubmed/37370935
http://dx.doi.org/10.3390/diagnostics13122040

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