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Neuronal p58(IPK) Protects Retinal Ganglion Cells Independently of Macrophage/Microglia Activation in Ocular Hypertension

p58(IPK) is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α kinases involved in a wide range of cellular processes including protein synthesis, ER stress response, and macrophage-mediated inflammation. Systemic deletion of p58(IPK) leads to age-related loss of retinal ga...

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Detalles Bibliográficos
Autores principales: McLaughlin, Todd, Wang, Jinli, Jia, Liyun, Wu, Fuguo, Wang, Yaqin, Wang, Joshua J., Mu, Xiuqian, Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297187/
https://www.ncbi.nlm.nih.gov/pubmed/37371028
http://dx.doi.org/10.3390/cells12121558