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Neuronal p58(IPK) Protects Retinal Ganglion Cells Independently of Macrophage/Microglia Activation in Ocular Hypertension
p58(IPK) is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α kinases involved in a wide range of cellular processes including protein synthesis, ER stress response, and macrophage-mediated inflammation. Systemic deletion of p58(IPK) leads to age-related loss of retinal ga...
Autores principales: | McLaughlin, Todd, Wang, Jinli, Jia, Liyun, Wu, Fuguo, Wang, Yaqin, Wang, Joshua J., Mu, Xiuqian, Zhang, Sarah X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297187/ https://www.ncbi.nlm.nih.gov/pubmed/37371028 http://dx.doi.org/10.3390/cells12121558 |
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