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Inverse Regulation of Cartilage Neogenesis at Physiologically Relevant Calcium Conditions by Human Articular Chondrocytes and Mesenchymal Stromal Cells

Elaborate bioreactor cultivation or expensive growth factor supplementation can enhance extracellular matrix production in engineered neocartilage to provide sufficient mechanical resistance. We here investigated whether raising extracellular calcium levels in chondrogenic cultures to physiologicall...

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Detalles Bibliográficos
Autores principales: Hammersen, Tim, Buchert, Justyna, Zietzschmann, Severin, Diederichs, Solvig, Richter, Wiltrud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297224/
https://www.ncbi.nlm.nih.gov/pubmed/37371129
http://dx.doi.org/10.3390/cells12121659