Chitosan Hydrogel-Delivered ABE8e Corrects PAX9 Mutant in Dental Pulp Stem Cells

Hypodontia (dental agenesis) is a genetic disorder, and it has been identified that the mutation C175T in PAX9 could lead to hypodontia. Cas9 nickase (nCas9)-mediated homology-directed repair (HDR) and base editing were used for the correction of this mutated point. This study aimed to investigate t...

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Detalles Bibliográficos
Autores principales: Liu, Bowen, Zhang, Chenjiao, Zhao, Han, Gao, Jian, Hu, Jingchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297230/
https://www.ncbi.nlm.nih.gov/pubmed/37367107
http://dx.doi.org/10.3390/gels9060436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297230/
https://www.ncbi.nlm.nih.gov/pubmed/37367107
http://dx.doi.org/10.3390/gels9060436

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