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Novel Isolation Method Reveals Sex-Specific Composition and Neurotoxicity of Small Extracellular Vesicles in a Mouse Model of Alzheimer’s Disease

We developed a new method to isolate small extracellular vesicles (sEVs) from male and female wild-type and 5xFAD mouse brains to investigate the sex-specific functions of sEVs in Alzheimer’s disease (AD). A mass spectrometric analysis revealed that sEVs contained proteins critical for EV formation...

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Detalles Bibliográficos
Autores principales:	Elsherbini, Ahmed, Zhu, Zhihui, Quadri, Zainuddin, Crivelli, Simone M., Ren, Xiaojia, Vekaria, Hemendra J., Tripathi, Priyanka, Zhang, Liping, Zhi, Wenbo, Bieberich, Erhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297289/ https://www.ncbi.nlm.nih.gov/pubmed/37371093 http://dx.doi.org/10.3390/cells12121623

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