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The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) signaling pathway has been implicated in various immune-mediated inflammatory and hyperproliferative dermatoses such as acne, atopic dermatitis, alopecia, psoriasis, wounds, and vitiligo, and is associated...

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Detalles Bibliográficos
Autores principales: Roy, Tithi, Boateng, Samuel T., Uddin, Mohammad B., Banang-Mbeumi, Sergette, Yadav, Rajesh K., Bock, Chelsea R., Folahan, Joy T., Siwe-Noundou, Xavier, Walker, Anthony L., King, Judy A., Buerger, Claudia, Huang, Shile, Chamcheu, Jean Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297376/
https://www.ncbi.nlm.nih.gov/pubmed/37371141
http://dx.doi.org/10.3390/cells12121671